Depression is an illness that, if left untreated, can last for years. This condition is increasingly common and can cause changes in the brain, as shown by research led by Jeff Meyer of the Campbell Family Mental Health Research Institute, published in The Lancet Psychiatry.
This study is about neuroinflammation, a physiological response of the brain when injury and illness occur. Thus, by reviewing brain images, the study has evaluated inflammation in psychiatric disorders, including depressive disorder, schizophrenia, and disorders.
Research shows as a result that those people who have had longer periods of depression not treated for more than a decade, had increased brain swelling compared to those who had less than ten years of untreated depression, as reported by Infosalus.
Thus, the study shows for the first time the evidence for inflammation in the brain in clinical depression, that is, brain changes in long-term depression. Conclusion, research explains that this would be a different stage of the disease that needs other therapies, a perspective similar to that given for the early and later stages of Alzheimer’s disease.
Currently, depression, Regardless of how long a person has been ill, it is treated with the same approach. Therefore, the different treatment options for this later stage of depression, such as specific medications for inflammation, are being investigated by this author and other experts.
For the investigation, cwith the participation of 25 people with more than ten years of depression, 25 with less than ten years of illness and 30 people without depression as a comparison group.
The levels of the inflammation marker that can be observed in the images studied were approximately 30% higher in different brain regions among those with long-term untreated depression versus those with shorter periods of untreated depression.
These new investigations could mean that medications designed for inflammation are used in other diseases in long-term depressive disorder.